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Diabetic Medicine, 29 (12), 1475-1481

Side effects vary by peptide but are generally mild

doi: 10.1007/s12031-025-02384-x 214 ChenLMinJWangF

Histamine acts as a neurotransmitter involved in the contractions of the intestinal muscles.[ref] People with food allergies and IBS had significantly higher levels of H1 and H2 receptors in their intestines.[ref] Histamine receptors in the brain: A 2026 study explored the role of histamine and histamine receptors in different regions of the brain